Small Randomized Trials

Blindness in Randomized Controlled Trials

In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...

Predicting Counterfactuals from Large Historical Data and Small Randomized Trials

When a new treatment is considered for use, whether a pharmaceutical drug or a search engine ranking algorithm, a typical question that arises is, will its performance exceed that of the current treatment? The conventional way to answer this counterfactual question is to estimate the effect of the new treatment in comparison to that of the conventional treatment by running a controlled, randomi...

blindness in randomized controlled trials

in combination with randomization, blinding or masking is an important factor in randomized controlled trials (rcts), particularly in trials that assess therapeutic effects. here an attempt is made to explain blindness and why it is important. in clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...

Cluster Randomized Trials and Equivalence Trials

Cluster Unit Randomized Trials